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結核病
推薦老師：流行病學與預防醫學研究所林先和老師

        結核病(Tuberculosis)是人類社會中存在已久的古老疾病，即便在醫療發達的二十一世紀，全世界每年依然有超過八百萬名的新增個案，並且造成超過一百四十萬人死亡。在台灣，2011年新增的個案數仍然超過一萬兩千人；雖然整體趨勢正在下降，但是下降的幅度趨緩。除了居高不下的發生率與盛行率之外，抗藥性結核病以及與愛滋病的共同感染，更是診斷與治療上的重大挑戰。為了達成根除結核病的目標，除了仰賴正在開發中的新一代疫苗、藥物以及診斷工具之外，跨領域的切入思考包括臨床與基礎醫學、公共衛生、醫療人類學等，更是不可或缺。

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編號 書名 / 作者 出版社 出版年 索書號 適用等級 摘要
1 Antituberculosis chemotherapy / volume editors, Peter R. Donald, Paul D. van Helden Karger 2011 WF360 A6338 2011 e-book Advanced bookpic This volume in the Progress in Respiratory Research series covers multiple aspects of the treatment of tuberculosis. The main purpose is to disseminate information about the treatment of tuberculosis in adults and children in order to improve the management of this infection worldwide. With multiple challenges in the treatment of tuberculosis, especially in the setting of coinfection with the human immunodeficiency virus and resistance to tuberculosis medications, this objective is commendable. This book will appeal to clinicians involved in the management of adults and children with tuberculosis, but the emphasis on antituberculosis treatment comes at the expense of other aspects of tuberculosis (clinical presentations, diagnostic tests).
2 Bovine scourge : meat, tuberculosis and public health, 1850-1914 / Keir Waddington  Rochester 2006 SF967.T8 W33 2006 Basic bookpic By the late 1890s, the question of bovine tuberculosis (TB) and infected meat had become one of national importance, reflecting a national sense of fear. Although the extent of the threat to health proved uncertain, bovine TB had come to stand at the centre of debates about diseased meat and public health. The anxiety it caused was part of a longer story, linked to concern over food safety, changes in how tuberculosis was understood, and to worries over diseased meat and the 'evils' of the urban meat trade. The Bovine Scourge explores the debates and fears that came to surround bovine TB, meat and public health between the 1860s and 1914. It traces how diseased meat and bovine TB emerged as a public health issue, examines the measures adopted to protect the public, and addresses how by the Edwardian era milk had become the major source of concern in discussion of bovine TB. It also raises important questions about the history of food safety, the concerns generated by diseased meat, and the role of the public health and veterinary profession in preventing the sale of contaminated food.
3 Cases in field epidemiology : a global perspective / edited by Mark S. Dworkin Jones and Bartlett 2010 WA105 O94 2011 Basic bookpic This collection of case studies—some never before published—uncover the details of actual disease outbreaks from within the United States and around the world. At the conclusion of each chapter, the investigator reviews the methods and processes that were employed to execute the investigation. Ideal as a complement to any text on infectious disease epidemiology, these case studies will bring to life the classic functions of field epidemiology and the application of epidemiological methods to unexpected health problems that require fast, on-site investigation and timely intervention. The cases cover investigations in infectious and non-infectious disease outbreaks, as well as environmental health related disease outbreaks.
4 Clinical tuberculosis / edited by Peter D.O. Davies, Peter F. Barnes, Stephen B. Gordon Hodder Arnold 2008 WF200 C641 2008 Advanced bookpic Over three previous editions, Clinical Tuberculosis has established itself as an indispensable guide to all aspects of tuberculosis diagnosis and treatment. This fully revised and updated fourth edition provides practical guidance to healthcare professionals involved in any aspect of patient management or disease control; chapters are included on epidemiology, pathology, immunology, disease presentation, diagnosis, treatment and management options. The problem of TB associated with HIV infection is given special emphasis, as are the increasing problems of multi-drug resistant strains and environmentally opportunistic mycobacteria. Chapter authors have been hand-picked to represent the most up-to-date thinking in their particular subject areas, making Clinical Tuberculosis the essential reference work for the bookshelves of respiratory physicians, infectious disease specialists, public health workers and other individuals involved in the management and control of tuberculosis worldwide.
5 Diagnostics for tuberculosis : global demand and market potential / TDR, FIND SA World Health Organization 2006 WF220 D5366 2006  e-book Advanced bookpic In this report, the World Health Organization's Special Program for Tropical Diseases Research (TDR), in collaboration with the Foundation for Innovative New Diagnostics (FIND), has compiled existing epidemiological data and generated a wealth of new data on the availability of TB laboratory services, variations in physician diagnostic practices, workloads of national laboratory networks, and manufacturer's sales to authoritatively document the volume and market value of TB diagnostic testing in nearly 200 countries. Customer requirements and R& D opportunities are clarified and the major scientific, financial, and market entry challenges specific to TB diagnostic development are presented alongside short and long term strategies and solutions. Furthermore, the potential future TB diagnostic market is estimated for a range of hypothetical new diagnostic tests covering the three major testing indications. Fourteen countries are profiled in detail to complement the global perspective.
6 Ecology of mycobacteria : impact on animal's and human's health / by Jindrich Kazda ... [et al.]  Springer 2009 QW125.5.M9 K23 2009 e-book Basic bookpic The Ecology of Mycobacteria principally emphasizes the ecological characteristics of the environmental mycobacteria. It is now well understood that the incidence and prevalence of potentially pathogenic mycobacteria is increasing in humans and animals. Further, proof that mycobacteria are normal inhabitants of drinking water distribution systems and household water systems, indicates that humans and animals are surrounded by mycobacteria and thus at risk. It is anticipated that the emphasis on ecology and routes of infection will result in a text of widespread use for clinicians and for research scientists in medicine, academia, and industry. In addition to identifying habitats and thereby sources of mycobacteria infecting humans and animals, the text identifies those mycobacterial characteristics that determine its range of habitats. Additionally, the text comments critically on the available methods to identify those protocols with values in mycobacterial research. In that manner, although there are no chapters specifically devoted to methods, superior methods for mycobacteria will be identified.
7 Electronic recording and reporting for tuberculosis care and control  World Health Organization 2012 WF200 E385 2012 Advanced bookpic Adopting electronic recording and reporting is not simply about choosing a piece of software: it is also about changing how people work. This is not a simple undertaking. This document introduces the key questions to be considered and illustrates what the questions, options and recommendations mean in practice by drawing on examples of recent experience from a variety of countries. It is an essential resource for all those planning to introduce electronic recording and reporting systems for TB care and control, or to enhance existing systems.
8 Global tuberculosis control : surveillance, planning, financing : WHO report World Health Organization 2010 WF300 G5626  2010 Basic bookpic This report includes the same wealth of information as previous reports in the series, but three new features are worth highlighting. First, the data are more up-to-date than those included in previous reports. Data up to and including 2009 are presented for almost all key indicators; financial data extend to 2011. Second, results from several analyses undertaken for the first time in 2010 are included. Examples are: (i) for each of the 22 high-burden countries (HBCs), trends in rates of TB incidence and mortality since 1990 combined with projections of whether the target of halving the 1990 mortality rate by 2015 will be achieved; (ii) estimates of the lives saved by TB control between 1995 and 2009 and projections of the additional lives that could be saved up to 2015, including separate estimates for women and children; (iii) assessment of progress in implementing and financing TB care and control against the targets included in a just-released and updated version of the Global Plan to Stop TB; and (iv) a new and compelling compilation of data showing the contribution that PP PP M can make to case detection.
9 Guidelines for the programmatic management of drug-resistant tuberculosis : [emergency update 2008] / [Steering Group, Ernesto Jaramillo ... et al.]  World Health Organization 2008 WF310 G946 2008 e-book Advanced bookpic The emergence in 2006 of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. These important developments and the availability of new evidence related to the diagnosis and management of drug-resistant tuberculosis have mandated an urgent update of existing guidelines. Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis: Emergency Updated Edition 2008 replaces previous publications by the World Health Organization on this subject. The Guidelines offer updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.
10 Handbook of tuberculosis Wiley 2008 WF200 H2353 2008 v.1-3 Basic bookpic Coinciding with the first TB therapies to enter clinical trials in 60 years, this is the most comprehensive account of the latest developments in clinical, therapeutic and basic research into the disease, presented by the most prolific of all researchers in the field. Divided into three clearly structured volumes, the first deals with molecular biology and biochemistry of the pathogen, including genetics and genomics, as well as drug design. The second volume covers cell biology, immunology and vaccine development, while the third is devoted to epidemiology and clinical approaches, including drug resistance, veterinary aspects and clinical field trials. With one new infection worldwide every second, this is an essential reference for bacteriologists, immunologists, pathologists and pathophysiologists, molecular and cell biologists, as well as those working in the pharmaceutical industry.
11 Infectious disease epidemiology : theory and practice / [edited by] Kenrad E. Nelson, Carolyn F. Masters Williams Jones and Bartlett 2007 WC100 I4026 2007  Advanced bookpic SARS, West Nile Virus, Avian Flu, and bioterrorism-related Anthrax are among the many infectious diseases that dominate the discussion among public health officials and policy makers today. This timely revision of Infectious Disease Epidemiology has been thoroughly updated to cover these and many other contemporary issues in infectious diseases.
12 Modern infectious disease epidemiology : concepts, methods, mathematical models and Public Health / Alexander Kramer, Mirjam Kretzschmar, Klaus Krickeberg, editors Springer 2010 WC100 M6894 2010 e-book Advanced bookpic Hardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro’s and con’s of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and overreaction of the public, we need solid scientific knowledge and an understanding of all aspects of infectious diseases and their control.The aim of our book is to present the reader with the general picture and the main ideas of the subject. The book introduces the reader to methodological aspects of epidemiology that are specific for infectious diseases and provides insight into the epidemiology of some classes of infectious diseases characterized by their main modes of transmission.
13 Molecular tools and infectious disease epidemiology / Betsy Foxman Academic 2012 WC100 F795 2012 e-book Advanced bookpic The application of modern molecular genetic and biologic techniques to infectious disease epidemiology dramatically improves measurement of disease and putative risk factors increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. We examine these opportunities and methodologic challenges giving specific examples. The book will be written for the reader with limited understanding of genetics, biology and epidemiology
14 Mycobacteria protocols / edited by Tanya Parish and Amanda Claire Brown Springer 2008 QW125.5.M9 M9952 2008  Advanced bookpic A collection of cutting-edge techniques for anyone interested in studying the molecular biology of mycobacteria, a medically significant organism responsible for both human and animal disease, including tuberculosis and leprosy. The book describes the basic techniques required for any study of mycobacteria, as well as providing methods for introducing DNA, for creating mycobacterial mutants, for obtaining defined gene knockouts by homologous recombination in both fast and slow growing species, for gene regulation and expression, for diagnostic purposes in detecting drug resistance, and for culture.
15 Pathogenesis of human pulmonary tuberculosis : insights from the rabbit model / Arthur M. Dannenberg  ASM 2006 WF300 D188p 2006 e-book Advanced bookpic Pathogenesis of Human Pulmonary Tuberculosis updates and revises the ground-breaking work of Max B. Lurie, summarizing the combined 80 years of research by Drs. Lurie and Dannenberg. This work examines the pathogenesis of human pulmonary tuberculosis in all of its stages, with a primary focus on the rabbit model, and offers a comprehensive resource for clinicians, public health investigators, and laboratory researchers in tuberculosis and immunology. Other animal models–mouse, guinea pig, and monkey–are compared with the rabbit and human models.
16 Treatment of tuberculosis : guidelines World Health Organization 2010 WF360 T784 2010  e-book Advanced bookpic The World Health Organization's Stop TB Department has prepared this fourth edition of Treatment of Tuberculosis: Guidelines, adhering fully to the new WHO process for evidence-based guidelines. Several important recommendations are being promoted in this new edition. This fourth edition confirms prior WHO recommendations for drug susceptibility testing (DST) at the start of therapy for all previously treated patients. Finding and treating multidrug-resistant TB (MDR-TB) in previously treated patients will help to improve the very poor outcomes in these patients. New recommendations for the prompt detection and appropriate treatment of (MDR-TB) cases will also improve access to life-saving care. This edition strongly reaffirms prior recommendations for supervised treatment, as well as the use of fixed-dose combinations of anti-TB drugs and patient kits as further measures for preventing the acquisition of drug resistance.
17 Tuberculosis : a comprehensive clinical reference / [edited by] H. Simon Schaaf, Alimuddin I. Zumla ; co-editors: John M. Grange ... [et al.] Saunders 2009 WF200 T8803 2009 Advanced bookpic This comprehensive textbook on tuberculosis covers the history, basic science, natural history, clinical features and management, prevention, and social issues while using illustrative cases. The purpose is to provide an up-to-date, affordable, and comprehensive review of tuberculosis in adults and children. The book is authored by clinicians and researchers from around the world, with an emphasis on the experience of providers in areas where multidrug-resistant tuberculosis (MDR-TB) and HIV/TB coinfection are major problems. This will appeal to a variety of readers, including clinicians, researchers, policy makers, and donor agencies, who will find relevant and detailed information. The authors are all respected experts in tuberculosis. The major emphasis is on the clinical management of tuberculosis, including in special populations such as children, pregnant women, and patients with HIV/TB coinfection. This is a newcomer to the world of textbooks of tuberculosis. It has a competitive edge because of its use of authors from different regions around the world, which gives a more international flavor and has extra appeal to readers in developing countries.
18 Tuberculosis and nontuberculous mycobacterial infections / edited by David Schlossberg ASM 2011 WF200 T8792 2011 e-book Advanced bookpic This is a complete and user-friendly review of tuberculosis and nontuberculous mycobacterial infections. The previous edition was published in 2006. With the multiple issues in the management of tuberculosis, especially with the emergence of antimicrobial resistance and the discovery of new nontuberculous mycobacterial infections, just to name a few of the challenges faced by clinical practitioners, a book like this is needed. According to the authors, the book is designed to be helpful to clinicians, epidemiologists, and scientists involved in the diagnosis and treatment of tuberculosis. The book will be more appealing to clinicians than scientists, who might be more interested in books that provide more robust information on molecular biology and pathogenesis of tuberculosis (e.g., the three volumes of the Handbook of Tuberculosis, Kaufmann et al. (Wiley, 2008). The authors are leaders in tuberculosis, and primarily based in the U.S. I wish the authorship was more global.
19 Tuberculosis prevalence surveys : a handbook World Health Organization 2011 WF300 T885 2011 Advanced bookpic The first edition of this book Assessing Tuberculosis Prevalence Through Population-Based Surveys was published by the World Health Organization in 2007. Its aim was to provide guidance to countries about how to estimate the prevalence of tuberculosis (TB) disease through population-based surveys. Designed for TB experts, survey investigators, researchers and advisers at national and international levels, the "red book" (as it soon came to be known) explained the core survey methods, including calculation of sample sizes, strategies for screening and diagnosis, case definitions, field operations, and how to analyse and report results. This second (lime) edition will help users to justify, design, fund, implement and analyze a high-quality national TB prevalence survey; to repeat surveys that allow comparisons with earlier surveys; to maximize the value of the data collected during surveys; and to ensure standardization of methods across multiple surveys in more than 20 countries in WHO s African, Eastern Mediterranean, South-East Asia and Western Pacific regions.
20 國際衛生 / 張武修等作 ; 張武修主編 華杏 2012 412 6072-1  Basic bookpic 全書共16章，作者均為過去數年間臺灣國際衛生實務的參與者。重點內容包括國際衛生簡介、國際基層醫療經驗、國際衛生計畫規劃與評估、衛生治理與社會安 全；世界衛生組織（WHO）、千禧年發展目標（MDGs）、亞太經合會（APEC）、非政府組織（NGOs）、菸草控制框架公約（FCTC）、國際衛生條 例（IHR）的沿革與介紹；愛滋病、結核病、流感所造成的全球衛生威脅，以及對經濟社會發展與國際衛生、國際醫療人道援助與全球衛生外交的闡述。含國際衛 生大事紀年誌，清楚呈現自1865年至今的國際衛生事件；並附有WHO衛生相關地圖，輔助說明近年相關議題趨勢。各章末特別附有延伸探討議題，期能帶給國 際衛生教育更多的刺激與啟發。
21 結核病防治工作手冊 / 行政院衛生署疾病管制局編 行政院衛生署疾病管制局 2009 412.452026 2440 2009  Basic bookpic 疾病管制局經全面檢討現行結核病工作流程並考量實務執行情形後，重新編訂第二版結核病防治工作手冊。內容包括修訂之結核病疾病介紹、通報登記及管理、都治 策略、接觸者檢查、結核菌檢驗、防治資源、強制隔離治療、飛航管制及處理、疑似聚集感染事件處理、X光巡迴檢查、卡介苗預防接種，並新增多重抗藥性結核病 照護及潛伏結核感染之治療。相信本手冊可提供公衛領域及醫療院所工作夥伴們實用的標準作業流程，並期待透過各界的通力合作，我國結核病十年減半的目標，可 如期達成。
22 結核病診治指引 / 陸坤泰主編 ; 行政院衛生署疾病管制局編  行政院衛生署疾病管制局 2011 415.277 2440 2011 Basic bookpic 為了提昇臨床醫師對結核病的診治水準，本局復邀請專家參考世界衛生組織最新出版International Standards for Tuberculosis Care和Treatment of Tuberculosis，以及美國Centers for Disease Control和American Thoracic Society出版的Treatment of Tuberculosis等指引，並依國內結核病治療情形撰編本指引，期許國內醫師在診斷治療結核病時，有標準統一的原則可茲遵循，除就原有內容再作補充 及更新，並廣徵內科醫學會、胸腔醫學會、感染醫學會、結核病醫學會、小兒科醫學會及家醫科醫學會等意見後予以印製，全書內容兼顧簡要與完整原則，希望提供 醫師們更完善實用的參考指引。
23 愛無國界 : 法默醫師的傳奇故事 / 崔西.季德(Tracy Kidder)著 ; 錢基蓮譯 天下遠見 2005 419.952 3463 4424 Basic bookpic 本書作者季德為1993年普立茲文學獎得主，透過他細膩的觀察和描述，哈佛大學醫學院傳染病學教授法默醫師的精采故事躍然紙上，讀來欲罷不能。擁有哈佛大 學醫學與人類學雙料博士的法默醫師，每年有四個月在波士頓看病、教學，其他時間則都在海地照顧窮病之人，治過的疾病可能比美國大多數醫師一輩子看過的還 多。他也到秘魯照顧結核病和瘧疾病人，後來又到古巴協助促進公共衛生，還說服了世界衛生組織（WHO）及世界銀行提供大量金錢，改善了西伯利亞監獄結核病 大量爆發的危機。法默醫師不屈不撓地奔走世界各地籌募捐款，讓窮人也能接受醫療，有個愛滋病人形容得貼切：「這傢伙是個聖人。」他的生命光輝，常人雖不能 及，但絕對會受到啟發和感動。
24 臺灣健康傳播之研究 : 以<<民生報>>1985-2005年肺結核、愛滋病、SARS、禽流感議題建構之內容分析為例 / 秦美婷著 唐山 2007 412.9232 5084 Basic bookpic 媒介、醫療體系，何者是信源權力的主導者？面對傳染病危機信息的傳播，政府如何掌握話語權？肺結核、愛滋病、SARS、禽流感疫情的發生，我們學習了什 麼？台灣是否是實踐「健康傳播」的最佳場域？上述問題，本書將帶領讀者從媒體的角度解讀媒體，從新聞撰述的內容中發覺問題的真相，在歷史的光譜下逐一見證 我們對抗傳染病的故事。本書在健康傳播領域中展開新的研究成果。作者以？民生報？在台21年為研究標的，針對四大傳染病之3299則新聞做全樣本的分析， 試圖建立媒體「健康傳播」的評估指標，分析媒體內部及外部信源權力的結構，進而建立「台灣健康傳播發展模式圖」。
25 聽,希望在唱歌 : 「愛與接納」傳染病病患的故事 / 行政院衛生署疾病管制局編  行政院衛生署疾病管制局 2006 415.2307 1440  Basic bookpic 本書敘述12位傳染病病患的患病過程與和社會互動的經歷，分別是7位愛滋病患者與5位肺結核患者，從他們自立自強與得到來自家人、朋友、醫師、支持團體、 政府相關單位的愛與接納，終於度過人生難關；尤其以許多實例釐清一般人對愛滋病與肺結核在傳染途徑與傳染方式上的錯誤認知，導入正確衛教知識，使大眾不再 無知地恐懼傳染病，恢復病患應有的人權。12篇故事讀來溫馨感人，極具啟示與教育意義。