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動脈硬化與心臟衰竭
推薦老師：內科賴凌平醫師

        心血管疾病是現代化社會的重要健康問題，而在臺灣地區，隨著社會的現代化，心血管疾病也已經連續數年蟬連國人十大死因的前幾名。

        近年來，醫學界在心血管疾病的研究及治療方面，都有不少的進步，這雖然解決不少重要的問題，然而在進步之餘，也引發更多新的問題，以及一些精益求精的研究，例如高血脂、高血壓、心臟衰竭、心房顫動及分子心臟學等，都是當前最熱門的研究題目。 

        自5月26日至7月21日起師長推薦圖書專區，以「動脈硬化與心臟衰竭」作為展出主題，懇請本院內科賴凌平醫師，推薦與展出主題相關的圖書，希望能引發讀者的興趣及共鳴，一同注意心血管疾病的重要性。

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編號 書名 / 作者 出版社 出版年 索書號 適用等級 摘要
1 Aging issues in cardiology / edited by Irene D. Turpie and George A. Heckman Kluwer Academic 2004 W3 D492 v.250 2004 Basic bookpic Book Description Aging Issues in Cardiology provides an overview of the practical clinical areas involved in managing cardiovascular disease in the elderly. This volume will be useful to any physician managing the cardiovascular health of elderly individuals. Topics covered include: - Delirium in Elderly Cardiac Patients, - Depression, - Pharmacologic Issues, - Primary Prevention, - Syncope, - Heart Failure, - Coronary Revascularization.
2 Atherosclerosis : diet and drugs / editor, Arnold von Eckardstein ; contributors, J. Ahrens ... [et al.] Springer 2005 QV25 H361 v.170 2005 Basic bookpic Book Description Book Description This book gives an overview on important mechanisms involved in atherosclerosis and thereby presents targets some of which are used and others which may be useful for therapy and prevention of atherosclerosis. Since atherosclerosis is a multifactorial disease the scientifc approach must be multidisciplinary. Accordingly, the authors of this book represent different areas of methodology ranging from basic, clinical and population research as well as different fields of expertise ranging from metabolism to immunology and inflammation biology and to vascular biology.
3 Atherothrombosis and coronary artery disease / editors, Valentin Fuster, Eric J. Topol, Elizabeth G. Nabel Lippincott Williams & Wilkins 2005 WG550 A8699 2005 Basic bookpic Book Review Most of us walk around oblivious to the time bombs that line our arteries. Indeed, atherosclerosis is, for the most part, a rather benign condition that affects, to some degree, virtually all the adult population both in developed countries and in many developing countries. Many adults will die from other causes before atherosclerosis causes overt problems. If the plaque is big enough and sitting in a coronary artery, it may impede blood flow and cause symptoms of angina. But if it is small, the plaque will usually be asymptomatic until the moment it supports thrombosis. The central role of thrombosis in the evolution of atherosclerotic plaque and the denouement in an acute cardiovascular event are well reflected in the title of this impressive book, and the interplay between plaque and thrombus is one of its central themes. Medical interest in atherosclerosis stretches back at least four centuries, and the book starts with a fascinating history of the disease that should be of interest to many. The mention of Heberden's classic description of angina pectoris reminds us that angina was a common condition in 18th-century London, and W. Bruce Fye's exhortation to reflect on the question, "Where does the review of the literature end and history begin?" — which Fye poses in the first chapter — provides the perfect start to a book that is intended to present the latest views in an area of fast-moving research. The following chapters cover the science of the disease and clinical practice, and the reader can find illustrations ranging from meta-analyses and Kaplan–Meier survival curves to schematic representations of a model of ATP-binding cassette transporters. Indeed, one of the greatest strengths of this book is the breadth of what is covered, and by selecting some of the leaders in the field as authors, the editors have provided the necessary authority to the writing, even if styles change from section to section. Breadth is important in an era in which doctoral students frequently find themselves working on highly focused projects dissecting a small piece of the puzzle. Even within a small area, subspecialization is becoming increasingly common. I shudder to recall the graduate student who, when asked in an examination how a blood vessel in a particular experiment was contracted before vasorelaxant agents were available, responded, "But my thesis is about dilatation, not contraction." Reestablishing an integrated approach to understanding atherosclerosis and coronary artery disease is clearly important, and this book should be available in any laboratory working in the field. The chapter on mouse models of atherosclerosis will be of value to many. There is also a lot here for clinicians: clear and helpful explanations of pathophysiology, a dip into more controversial areas such as the effects of viruses on atherothrombosis, and informative sections on current therapeutic approaches. Flipping back and forth between the section on therapeutics and the historical perspective should help to keep the reader from becoming too convinced that we know exactly how to manage our patients' conditions, even in 2005. So, are there any problems? Of course, there are some inconsistencies and some omissions: Why, for example, is the important side effect of nocturia caused by calcium-channel blockers never mentioned? These minor flaws are not enough to detract from the quality and importance of the book, but I do have a gripe about the quality of the figures. We increasingly depend on visual images in order to learn, and yet the book is packed with rather dull black-and-white images. Some of those in chapter 19 even look as though they were poorly scanned or downloaded. The wonderful color plates in the middle of the book show what can be used, and it would have been nice to have figures of this quality throughout the book. The most important question, however, is whether I would buy this book. The answer is yes.
4 Cardiac markers / edited by Alan H.B. Wu ; foreword by William E. Boden Humana Press 2003 WG300 C2668 2003 Advanced bookpic Book Review Dr. Alan Wu once again presents us with important information concerning the rapidly evolving field of cardiac markers. As in his 1st edition of this book (1998), Dr. Wu presents a thorough review of this clinically relevant field. Again, nearly 50 experts—srepresenting the leading national and international academic centers—discuss in detail the specific diagnostic and prognostic uses of these markers in distinct cardiac (acute coronary syndromes, reperfusion injury, and post-aortocoronary bypass) and comorbid (renal failure and myositis) disease states. The book again provides detail on specific analytical issues, such as protein assay chemistry, cutoff criteria, and standardization, which are discussed with an eye towards understanding the rationale and limitations of the different marker assays. Additionally, this 2nd edition has added sections that elucidate the important laboratory, pathophysiologic, and clinical properties of both C-reactive protein and beta-type natriuretic peptide. The clinical evolution of these latter markers during the interval between the 1st and 2nd editions of this book underscores the pace of advancements in this field, and the importance of this current volume. The strengths of this text are many. First and foremost, the topics of interest that pertain to each cardiac marker are well organized, under detailed chapter headings. Within each chapter, the text is well supported with figures and tables in a style that is uniform throughout the book, and points within the text are annotated with specific references that facilitate review of the primary data by the reader. However, as clinicians, we found that the many clinically important topics were interspersed with those more applicable to biochemical researchers or laboratory medicine physicians. Because the scope of this text encompasses much more than is likely relevant to any single field, we think it improbable that the full text will maintain the interest of most readers. Accordingly, we feel that this text is better utilized as a reference work than as an educational review. In support of this role as a reference, the book has a relatively extensive and detailed index. In summary, this book is highly recommended as a reference resource for cardiologists, internists, emergency medicine physicians, and laboratory medicine physicians who have specific questions regarding the many clinically relevant cardiac markers. Given the current, concise, and highly organized content of this text, this reference will save the physician considerable time and effort in answering a specific question that he or she may have within this rapidly evolving field. However, given the incorporation of biochemical, laboratory, pathophysiologic, and historical details with clinically relevant topics, we hesitate to recommend this text as more than as an invaluable reference—unless one has a specific research interest in this field.
5 Cardiovascular disease in the elderly / edited by Gary Gerstenblith Humana Press 2005 WG120 C26733 2005 e-book Basic bookpic Book Review "Did [the editors] accomplish something more, presenting the unique multifactoral issues and needs that must be addressed to car for a geriatric patient? Yes indeed!" -Chest "I could not find a bad contribution from any of the authors, only very good and excellent….a 'must read' for anyone dealing with elderly patients." -The American Journal of Geriatric Cardiology "…will become core reading for every cardiologist." -William R. Hazzard, Director of Geriatrics and Extended Care, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, U.S.A. "…should be considered the premier reference source for clinicians and teachers in the field." -Journal of the American Geriatrics Society "...well organized and informative. It will be very useful to physicians who care for the elderly, both as background reading and as a reference for specific questions." -The New England Journal of Medicine "…The timely publication of this book is an attempt to help bridge the gap in our understanding of the pathophysiology of the disease." -CVR&R "…This book of 32 chapters by 52 contributors is surely the best one available on this topic." -The American Journal of Cardiology 　 Book Description Certain to become the most trusted source in geriatric cardiology, this Third Edition compiles the latest studies and expertise on the epidemiology, pathophysiology, and management of cardiovascular disease in the elderly patient-tracking the rapid pace of innovation in the field with in-depth explorations of the most recent clinical trials and advances in vascular biology, cardiology, and cardiovascular surgery for influential developments in disease prevention and management.
6 Current diagnosis & treatment in cardiology / edited by Michael H. Crawford Lange Medical Books/McGraw-Hill 2003 WG100 C9761 2003 Basic bookpic Book Review Doody's : "This book provides a focused review of general cardiology in 37 chapters from coronary artery disease to the athlete's heart. It is truly a good board review text. The book achieves its goal as a quick reference and as a basis for a board review. Although its size precludes extensive details, it is a good book that would find a place on every cardiology ward." 　 Book Description SAVES 15%! This value pack consists of CURRENT Diagnosis Treatment in Cardiology, 2/e and Essentials of Diagnosis Treatment in Cardiology both by Michael Crawford, MD.
7 Diabetes and cardiovascular disease / edited by Michael T. Johnstone, Aristidis Veves Humana Press 2005 WK835 D53345 2005 e-book Basic bookpic Book Description DEpidemiological studies have identified diabetes mellitus as a major independent risk factor for cardiovascular disease and show that 65% of patients with diabetes mellitus die from cardiovascular disease. This book comprehensively reviews both the basic and clinical aspects of diabetic vascular disease for the practicing clinician. Leading authorities cover the general aspects of diabetes mellitus, macrovascular disease and microvascular disease. Michael T. Johnstone, MD and Aristidis Veves, MD, DSc, have assembled a panel of seasoned clinicians and expert scientists to comprehensively review both the clinical and scientific aspects of diabetic cardiovascular disease. The contributors thoroughly discuss the mechanisms and risk factors of diabetes in relation to hypertension, dyslipidemia, thrombosis, atherosclerosis, coronary artery disease and congestive heart failure. 　 Book Info Harvard Medical School, Boston, MA. Offers clinicians and clinical scientists a comprehensive review of the clinical and scientific aspects of diabetic cardiovascular disease. Examines the effect of diabetes on the heart, and includes a full discussion of the macrovascular effects of the disease. DNLM: Diabetes Mellitus--complications. From the Publisher On the basic side, this book describes the pathophysiology of diabetic vascular disease and the methods are included to evaluate them. This book describes recent clinical study findings that Dr. Johnstone discusses in his own chapter. Diabetes and Cardiovascular Disease is in Humana's Contemporary Cardiology Series and covers the subject categories of Cardiology, Endocrinology and Diabetes, Internal Medicine and Physiology. Readership includes cardiologists, internists, vascular specialists, diabetologists, endocrinologists and family physicians. From the Author This book will be essential reading for all cardiologists, general internists, vascular specialists as well as medical students who are confronted with patients who have diabetes and cardiovascular disease. Covered are reviews of clinical aspects of diabetic cardiovascular disease, up-to-date clinical and scientific survey of the basic mechanisms of diabetic damage, full discussion of microvascular effects of diabetes mellitus and examination of diabetes' effects on the heart, including atherosclerosis and congestive heart failure.
8 Dietary proteins and atherosclerosis / G. Debry CRC Press 2004 QU55 D288d 2004 e-book Basic bookpic Book Description Dietary Proteins and Atherosclerosis provides a thorough review of the role of proteins in the development of atherosclerosis. The author reviews early research connections between dietary fat and cardiovascular disease caused by the build-up of plaque in arteries and examines other factors that contribute to atherosclerosis, such as infection and dietary proteins. Relying on data obtained from almost 2,000 research articles and literature reviews, the author provides a thorough analytical examination and discusses how emphasis on the role of dietary fat in atherogenesis has overshadowed the critical contribution of dietary proteins to the development of cardiovascular disease. 　 Book Information Summarizes and discusses the role dietary protein may play in the etiology of atherosclerosis and atherosclerotic heart disease. Encyclopedic in scope and summarizes virtually all aspects of the protein-atherosclerosis connection. Contains nearly 2,000 references including the latest research. DNLM: Dietary Proteins--adverse effects.
9 Exercise testing and exercise prescription for special cases : theoretical basis and clinical application / editor, James S. Skinner Lippincott Williams & Wilkins 2005 WB541 E955 2005 Basic bookpic Book Review The "Special Cases" of the title include such diverse medical or physiologic conditions as diabetes, obesity, asthma, coronary disease, pregnancy, or renal failure, to name a few. The editor, a Professor of Exercise Science and Physical Education, attempts to bridge the gap between clinicians, familiar with the medical conditions of their patients, and the exercise physiologist or technician who is called on to evaluate the patient, design an exercise prescription, or both. Toward this end, each of the chapters related to a particular medical condition (15 in all), beginning with an overview of the condition written in lay terms. Available information concerning exercise capacity or exercise function in patients with the condition follow. Since these exercise data derive from a variety of sources and were generated for differing purposes, there is an unavoidable lack of uniformity in the type of information about exercise function for the various conditions discussed. A series of six General Consideration chapters precede the Special Cases, addressing topics such as effects of gender on exercise function, effects of aging, differences between children and adults, and designing exercise prescriptions. Chapters are individually authored and are therefore somewhat variable in focus, tone, and currency. Most welcome, are those on topics for which an overview is not generally available in other exercise books such as pregnancy, renal failure, osteoporosis, congenital and valvular heart diseases, and obesity. Chapters on some of the conditions more commonly studied, and for which much data is available, are sometimes disappointing with respect to balance and to the integration of data from recent published literature.
10 Grossman's cardiac catheterization, angiography, and intervention / editor, Donald S. Baim Philadelphia Lippincott Williams & Wilkins 2006 WG141.5.C2 C267 2006 Basic bookpic Book Review The premier reference on cardiac catheterization is now in its thoroughly revised Seventh Edition, reflecting the rapid evolution and growing clinical use of interventional techniques. The completely revamped interventional section includes new material on treatment of pediatric and adult congenital heart disease, as well as on coronary atherectomy, thrombectomy, distal embolic protection devices, bare metal and drug-eluting stents, and percutaneous valve therapies. Other significantly revised chapters include pulmonary angiography, endomyocardial biopsy, and circulatory assist devices. This edition's companion DVD features more than 100 digital cases, plus more than 20 animations showing the actions of various invasive and interventional devices.
11 Handbook of cardiovascular cell transplantation / edited by Nicholas N. Kipshidze and Patrick W. Serruys Martin Dunitz 2004 WG169 H23565 2004 Basic bookpic Book Description Clinicians are now beginning to revascularize cardiac tissue damaged by myocardial infarction with transplanted cells. Though still in the early phases, such revascularization is currently being transformed from a research concept to a clinical tool. Various tissue types and genes are transplanted to improve left ventricular and systolic scar functions, and to prevent further deterioration of ejection fractions. The editors have assembled an expert team of international researchers and clinicians. Handbook of Cardiovascular Cell Transplantation is essential for cardiologists and cardiothoracic surgeons, and trainees who want to learn about the future of cardiovascular medicine. Book Information Lenox Hill Heart and Vascular Institute, New York City, NY. Presents updated experimental studies and first clinical trials exploring the use of a number of different cell types, including embryonic stem cells, cardiac myocytes, fetal and neonatal cardiomyocytes, skeletal myoblasts, and more. For researchers and practitioners. 　 Book Information Lenox Hill Heart and Vascular Institute, New York City, NY. Presents updated experimental studies and first clinical trials exploring the use of a number of different cell types, including embryonic stem cells, cardiac myocytes, fetal and neonatal cardiomyocytes, skeletal myoblasts, and more. For researchers and practitioners.
12 Handbook of echo-doppler interpretation / Edmund Kenneth Kerut, Elizabeth F. McIlwain, Gary D. Plotnick Blackwell Publishing 2004 WG141.5.E2 K41h 2004 Advanced bookpic Book Review "Each chapter is well laid out and it is easy to see where the text is leading. The authors have made good use of lists which are much clearer than wading through lines of unnecessary prose. The text is liberally interspersed with well annotated diagrams and illustrations. A picture can say a thousand words and this has been used to good advantage. Real-time ultrasound images and Doppler traces are plentiful, are of good quality and have been reproduced well. I was pleased to see that all the real-time ultrasound images are reproduced as negatives (white on black) although the illustration on the cover is a positive image! The authors have been successful in making this a practical handbook of echocardiography and interpretation. It is easy to read and very well illustrated. There is no attempt to relate echocardiography to other cardiac imaging modalities and this is no substitute for a cardiology textbook. Those new to echocardiography should find it helpful as they build up experience. The more experienced echocardiographer may find it useful to refer to specific chapters on unfamiliar subjects or use the references for further study. By today's standards this is good value for money and would be useful on the shelves of most departments. I suspect those new to echocardiography will consider purchasing their own copy."
13 Heart failure : a companion to Braunwald's Heart disease / [edited by] Douglas L. Mann Saunders 2004 WG370 H43618 2004 Basic bookpic Book Review This large textbook provides a complete up to date bench-to-bedside overview of the field of heart failure. The five sections progress from the basic molecular and cellular mechanisms that underlie heart failure, through mechanisms that lead to disease progression of heart failure, and the etiological basis for heart failure, to the clinical assessment and treatment of heart failure. Novel chapters that have not as yet been included in traditional textbooks are included on topics such as: the new and emerging area of sleep-disordered breathing and heart failure; the science of developing heart-failure guidelines; and clinical trial design in heart failure.
14 Heart transplantation / James K. Kirklin, James B. Young, David C. McGiffin Churchill Livingstone 2002 WG169 K589h 2002 Advanced bookpic From the New England Journal of Medicine, December 26, 2002 Heart Transplantation, a beautifully written, comprehensive monograph, sets new standards. The authors, long-term scientific leaders in the field, are optimally positioned for this task. Their book covers the topic in a consistent and carefully balanced way. Cardiac transplantation has rapidly evolved since the groundbreaking experimental work of Norman Shumway's group at Stanford in the 1950s and 1960s and the first transplantation of a human heart, performed by Christiaan Barnard on December 3, 1967, in Capetown, South Africa. Heart Transplantation captures every aspect of the subject, from the early experiments to the realization of a dream (which took its place in history alongside the landing on the Moon) and to contemporary practice. The authors of Heart Transplantation intend to provide in-depth coverage, including historical background, information about basic mechanisms, and discussion of clinical outcomes in the care of patients with advanced heart failure. At the same time, they aim to facilitate orientation to the subject and readability for a diverse audience -- the health care practitioner as well as the expert in cardiac transplantation. Kirklin, Young, and McGiffin introduce us to the field by honoring the breakthrough work of Alexis Carrel, Charles Guthrie, Shumway, and Barnard, among others. In 1965, Shumway, generally considered the father of clinical heart transplantation, prophetically commented, "For successful homotransplantation in man, it would be necessary to legally deprive of life both the donor, a hopeless brain injury for example, and the host whose own heart has not yet stopped beating. Considerable social, moral, and legal reformation must precede any serious clinical application of a challenging laboratory experiment." To establish the background for the main body of the book, there are sophisticated, easily understood introductions to transplantation immunology and the use of advanced statistical techniques for outcome research. After presenting this background material, the book moves on to topics including "The Patient before Transplantation," "The Transplanted Heart," "Management of the Transplant Patient," "Long-Term Outcome after Heart Transplantation," and "Special Situations in Heart Transplantation." Throughout, the reader will find hundreds of insightful comments and clinical recommendations based on the vast experience at the University of Alabama at Birmingham and the Cleveland Clinic Foundation. The strength of many of these recommendations is that they are based on the Cardiac Transplant Research Database, which in many respects is the best data set currently available. I would advise caution, however, about the degree to which results from centers of excellence represented in this data base can be translated to the average transplantation center. I would also advise caution about whether improved post-transplantation outcomes can be equated with gain in benefit for the individual patient in the absence of data on risk stratification with respect to the severity of heart failure at transplantation. A special highlight of the book is its seamless, interdisciplinary approach combining cardiology, surgery, and basic science. Another outstanding feature is the absence of redundancy, achieved by systematic cross-referencing and authoritative, expert editing and writing. What makes this book particularly welcome is its consistency in style; the integration of text, tables, and figures; and the well-designed special-interest boxes with optional background information, which facilitate the flow of thought in the main text. The extensive reference list (comprising more than 5000 references) provides a wealth of suggestions for further in-depth reading. Heart Transplantation sets the new standard with which subsequent books on this subject will have to be compared. Mario C. Deng, M.D. Copyright © 2002 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS. 　 Book Description This truly comprehensive reference is devoted to every aspect of heart transplantation. It not only covers the surgical procedures for the donor and recipient, but also explores pre and post operative patient management, operative techniques and non-surgical cardiac management options. The 3 reasons you need this book are: (1) Extensive outline and bolded phrases will provide you with QUICK and EASY access to the information; (2) Over 700 illustrations will provide an additional visual aid to enhance your understanding of the text; and (3) Access to information on all the most currently used immunosuppressive drugs and other modalities with helpful tables.
15 Hypertension in the elderly / edited by Michael L. Prisant Humana Press 2005 WG340 H99517 2005 Advanced bookpic Book Description Though it seems illogical to offer treatment to reduce cardiovascular risk factors in those with a limited life expectancy and inappropriate to lower blood pressure in the elderly when it is known that hypertension rises as people get older, studies have shown beyond reasonable doubt that lowering the blood pressure in the elderly reduces morbidity and prolongs life. Hypertension in the Elderly examines this subject in depth, including such topics as Measurement of blood pressure and postural hypotension, the benefits of treating hypertension in the elderly, lifestyle modifications and improving compliance. This comprehensive book includes color tables, algorithms, guidelines, and charts. --This text refers to the Paperback edition.
16 Improving outcomes in heart failure : an interdisciplinary approach / edited by Debra K. Moser, Barbara Riegel Aspen Publishers 2001 WG370 I34 2001 Basic bookpic Book Review Congestive heart failure often is the final pathway in a variety of cardiovascular disorders, and coronary artery disease has become the leading cause of congestive heart failure. Many risk factors for coronary artery disease also are predictors of hypertension, left ventricular hypertrophy, and diabetes mellitus. Currently, 4.9 million Americans live with congestive heart failure, and approximately 550,000 new cases are added each year. It is the most common cause of hospitalization for people age 65 or older. The incidence and prevalence of congestive heart failure are expected to grow because of recent declines in mortality for patients with coronary artery disease. Congestive heart failure is the single most costly cardiovascular illness in the United States because of increased prevalence and associated medical resource consumption. This journal-sized book is written by two editors of the Journal of Cardiovascular Nursing. Both are nationally recognized experts in the field of cardiovascular nursing. They have received numerous awards and honors and have contributed to many renowned journals on a wide variety of cardiovascular topics. Contributors to the book include cardiologists, professors of medicine and nursing science, dieticians, clinical scientists, and nurses from every field, including surgery, hospice, home health, and case management.
17 Integrated cardiology : from benchtop to clinic / [editor, Akira Kitabatake] Hokkaido University Graduate School of Medicine 2004 WG120 I61113 2004 Basic bookpic Book Review Cardiovascular disease,including stroke, is the leading cause of illness and death in Japan. In the past couple decades,considerable effort has been made to prolong survival and improve the quality of life of patients with cardiovascular diseases, and epidemiologic studies and randomized clinical trials have provided compelling evidence that coronary heart disease is large preventable. However,despite innovations in technology and pharmacology,cures are basically not available, partly because of poor understanding of the basic mechanisms responsible for these diseases. Information about the pathophysiology underlying cardiovascular diseases had not been available until the recent advances in molecular genetics revealing the genetic defects in some monogenic diseases,such as cardiomyopathy and congenital arrhythmias. With regard to complex traits in more common cardiovascular diseases,current research is focusing on the pathogenesis by integrating many technological advances from basic cardiology including molecular biology and genetics to clinical cardiology. These approaches are expected to provide tools to elucidate the fundamental mechanisms of cardiovascular diseases, opening new possibilities not only for improved therapeutic and diagnostic measures but also for prevention.
18 Ischemic stroke / editors, H.J.M. Barnett, Julien Bogousslavsky, Heather Meldrum Lippincott Williams 2003 W1 Ad95ne v.92 2003 Basic bookpic Book Description This timely book provides basic, practical and up-to-date information on how to use imaging to diagnose and treat patients with acute ischemic stroke. Written by physicians from the Massachusetts General Hospital and faculty from the Harvard Medical School, the book distills years of experience in the day-to-day management of acute stroke patients, as well as leading-edge basic and clinical research, into a practical guide. With the growing awareness that modern CT and MR imaging can meaningfully improve the outcome of the acute stroke patient, this book provides the practical information to advance the capacities of providers in delivering the most advanced care for this disease.
19 Lipids and atherosclerosis / edited by C.J. Packard and D.J. Rader ; foreword by V. Fuster Taylor & Francis 2006 WG550 L7653 2006 Basic bookpic Book Description New discoveries in genetics, molecular, and cell biology are not only enhancing our understanding of the etiology and progression of disease, but are finding applications in the development of new drugs or the implementation of new kinds of therapy. This book provides an in-depth review of emerging areas in biomedical research at the interface of science and clinical medicine. Written by a team of well-known experts, Lipidology: Translational Medical Science presents an authoritative overview of key advances in biomedical research and reviews the most important recent advances in lipidology, highlighting their relationship to cardiovascular disease.
20 Lower extremity arterial disease / edited by Dennis G. Caralis and George L. Bakris Humana Press 2005 WG510 L917 2005 e-book Basic bookpic Book Review A comprehensive review the state-of-the-art in atherosclerosis of the arteries of the legs and feet. The authors discuss in detail the primary symptom-claudication-an intermittent pain in the leg or foot while walking, its predisposing factors, the current diagnostic methodologies, the impressive advances in the therapeutic armamentarium, and the need to screen for co-existing coronary artery disease. Additional chapters describe cutting-edge noninvasive angiography and vascular flow studies, specific drug therapy for claudication, regression of atherosclerosis therapy, gene therapy, and drug eluting stents for peripheral arterial disease. The authors also examine the epidemiology of LEAD, the effects of smoking and effective smoking cessation programs, its pathogenesis and its association with lipid abnormalities and hypertension, aggressive risk factor modification, and the need to measure the ankle brachial index of every patient over 45.
21 New developments in cardiac pacing and electrophysiology / edited by I. Eli Ovsyshcher Futura Pub. Co 2002 WG168 N5311 2002 Advanced bookpic Book Description This book offers updated explanations for the electrophysiological basis of many arrhythmias, with an emphasis on atrial fibrillation. Distinguished experts address specific topics in their fields, gathering current, relevant information in a clear and user-friendly format. It reviews different aspects of bradyarrhythmias and discusses various pacing approaches to terminating tachyarrhythmias. It examines cardiac resynchronization therapy for patients with congestive heart failure, and elaborates on the use of the implantable cardioverter-defibrillator which is becoming an increasingly important therapeutic resource.
22 Peripheral arterial disease : diagnosis and treatment / edited by Jay D. Coffman, Robert T. Eberhardt Humana Press 2003 WG510 P4404 2003 Basic bookpic Book Description ...provides a detailed accounting of the medical, surgical, and radiological aspects of peripheral arterial obstructive disease, empowering today's clinicians and specialists. From the New England Journal of Medicine, July 3, 2003 Peripheral arterial disease and its associated mortality are increasing worldwide. Although bench and bedside research have been widely neglected and the disorder is often overlooked, interest in peripheral arterial disease is growing rapidly. Peripheral Arterial Disease supports this interest by pointing the way toward less invasive procedures that can be used to diagnose and treat this disease. "Noninvasive and endovascular approaches first" is the fiber that 27 well-known authors have threaded through 19 chapters covering the most important aspects of peripheral arterial disease. Chapters on the causes, epidemiology, pathology, pathogenesis, and natural history of peripheral arterial disease are followed by chapters on clinical aspects, diagnosis, and the management of the disease, as well as discussions of risk factors associated with treatment. The book also includes chapters on the special aspects of peripheral arterial disease in women and in patients with diabetic foot disease or vasculitis. The focus is clearly on peripheral arterial disease, since neither central and peripheral aneurysmal disease nor cerebrovascular and supra-aortic arterial disorders are covered adequately. The prevention of myocardial and cerebrovascular events and the use of antiplatelet therapy, on the other hand, receive extensive attention. The excellent disquisition on exercise rehabilitation, which is the most effective conservative treatment of peripheral arterial disease, is exemplary. This comprehensive textbook has a number of strengths. The editors have assembled as contributors a team of experts who emphasize the analysis of primary data from key studies in the field and who provide thorough reference lists. Besides chapters that deal with material that has already been presented in a number of books, readers will also find valuable chapters on subjects that are rarely seen elsewhere, such as the one on arterial vascular disease in women. Nearly every aspect of peripheral arterial disease is covered, providing a comprehensive overview but with the disadvantage of occasional superficiality in the chapters dealing with well-known modes of treatment. This blemish, however, can easily be overlooked in a readable book limited to just over 350 pages, and it is generously compensated for by the extensive discussion of emerging endovascular, genetic, angiogenic, and drug therapies for peripheral arterial disease. A small but sufficient number of well-labeled figures throughout the book facilitate comprehension. The book is dedicated to two distinguished vascular specialists who died last year. The chapters by these expert clinicians and investigators are the highlights of the book. Gene Strandness, of the University of Washington, developed diagnostic ultrasonographic techniques, and his chapter on arterial hemodynamics rests on a lifetime commitment to work in this area. He designed the first electric analogue model of the peripheral circulation, which is a great teaching tool. The book is also dedicated to Jeff Isner of Boston, who pioneered clinical applications of gene therapy. Peripheral Arterial Disease is an outstanding textbook -- less so for specialists, but all the more an excellent reference for students, residents, and general practitioners. On the bookshelves of scientists and clinicians in related disciplines and in multidisciplinary teams, this book will provide a state-of-the-art review of current knowledge of peripheral arterial disease, and it will undoubtedly remain an excellent reference for some years to come. Wolfgang Schaper, M.D., Ph.D. Copyright © 2003 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.
23 Principles of molecular cardiology / edited by Marschall S. Runge, Cam Patterson ; foreword by James T. Willerson Humana Press 2005 WG120 P957 2005 Basic bookpic Book Review An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart''s development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.
24 Renin angiotensin system and the heart / edited by Walmor C. De Mello John Wiley & Sons 2004 WG106 R413 2004 Basic bookpic Book Review "Recommended for the intended audience of cardiologists, nephrologists, cell and molecular biologists, physiologists, pathologists and pharmacologists as well as medical libraries." (E-STREAMS, May 2005) 　 Book Description Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function. It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone. •Contains the most recent findings on the renin angiotensin system and the heart •Written by an international team of distinguished scientists •Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research .
25 Surgical management of congestive heart failure / edited by James C. Fang, Gregory S. Couper ; foreword by Lynne W. Stevenson Humana Press 2006 WG169 S9615 2005 Advanced bookpic Fang, James C. (Brigham and Women's Hospital and Harvard Medical School, Boston, MA) Couper, Gregory S. (Brigham and Women's Hospital and Harvard Medical School, Boston, MA) James C. Fang, MD, and Gregory S. Couper, MD, have assembled a panel of prominent surgeons and cardiologists to review the latest clinical, scientific, and investigational surgical and mechanical approaches to heart failure in hopes of improving the lives of this challenging group of patients. Topics range from such traditional strategies as high-risk surgical revascularization in advanced coronary artery disease, to more novel approaches such as ventricular reconstruction and mechanical assist devices. Many chapters are contributed by the original pioneers of specific surgical techniques, which provide s invaluable perspective from personal experience.
26 Unraveling lipid metabolism with microarrays / edited by Alvin Berger, Matthew A. Roberts Marcel Dekker 2005 QU85 U589 2005 e-book Advanced bookpic Book Review Lipids play an important role in numerous physiological functions, including their structural role in cell membranes and their conversion to eicosanoids, which affect neighbouring cells through receptor interactions. New technologies are permitting rapid expansion of the understanding of lipids and one such technology is the microarray. This book presents a collection of reviews on microarray technology and provides guidance on handling omnic datasets. Each of the 19 reviews includes a summary and an extensive reference list. It is hoped that the book will encourage more scientists to use omnic techniques in their own fields of research.