推薦老師：眼科楊長豪老師
老年性黃斑部病變是造成中老年人視力喪失的重要病因。隨著台灣逐漸進入老年化社會，所以應該加強對此疾病的認識。
高齡是造成老年性黃斑部病變的原因之一，遺傳及環境的因素都可能扮演重要的角色，研究顯示基因中補體因子H如果產生變異則得病的機會增加。環境因素包括抽菸、高脂肪高熱量食物、合併心血管疾病等，都可能加重老年性黃斑部病變得病的機會。
老年性黃斑部病變的臨床表現分為萎縮型（乾式）及滲漏型（濕式）。乾式病程進展緩慢，目前尚無有效的治療方法。濕式則為脈絡膜長出新生血管，造成黃斑部的滲漏及出血，影響視力較大，目前以玻璃體內注射抗VEGF藥劑為主。另外移植幹細胞及視網膜晶片也在積極研究中。
有鑑於老年性黃斑部病變發生的比例勢必逐漸增加，歡迎大家一起加入老年性黃斑部病變的研究。
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| 編號 | 書名 / 作者 | 出版社 | 出版年 | 索書號 | 適用等級 | 摘要 |
|---|---|---|---|---|---|---|
| 1 | Age-related changes of the human eye / edited by Carlo Cavallotti, Luciano Cerulli | Humana | 2008 | WW140 A265 2008 e-book | Basic |
Aging research on the human eyes crosses all areas of ophthalmology and also relies upon biological, morphological, physiological, and biochemical tools for its study. In Age-Related Changes of the Human Eye, the authors review all aspects of human eye aging. In addition to descriptions of age-related changes in almost all the structures of the human eyes, the authors also include interesting accounts of personal experiments and data. The ease of use and versatility of this volume makes it an essential tool for students and graduate students as well as post-doctoral and/or professional ophthalmologists. Age-Related Changes of the Human Eye provides the reader with an exhaustive panorama of what happens during aging in the eye, thus making an important contribution to the understanding of the physiology and pathology of eye diseases. From Books In Print
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| 2 | Age-related macular degeneration / editors, D. Virgil Alfaro, III, Eric P. Jablon, John B. Kerrison… [et al.] | Wolters Kluwer | 2015 | WW270 A26493 2015 | Basic |
Stay up to date with the latest developments in your field with the highly-anticipated second edition of Age-Related Macular Degeneration. This comprehensive text covers recent advances in pathophysiology, diagnosis, and treatment including promising new developments that will affect your patient care. Dr. Virgil Alfaro and his colleagues at Retina Consultants of Charleston bring you their expertise in the areas of basic science, imaging, prevention, treatment, and more. Features: Learn from a renowned group of retina surgeons who address all aspects of management, including anatomy, physiology, and pathophysiology; imaging of the macula in ARMD, prevention measures and treatment; and future directions in the field. Gain a solid foundation in intravenous fluorescein angiography, indocyanine green angiography, and optical coherence tomography, as well as antiVEGE therapy and related new drugs, optimizing your diagnosis and treatment options. Understand the significant change in the classification system of choroidal neovascular membranes in ARMD. From Books In Print
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| 3 | Age-related macular degeneration / Frank G. Holz ... [et al.], editors | Springer | 2013 | WW270 A265 2013 | Basic |
Age-related macular degeneration is the most common cause for the loss of central vision beyond the age of 50 in industrial nations. Triplication of the number of affected patients is expected over the next 25 years. Especially over the last years the standard of knowledge regarding etiology, risk factors, diagnostics and therapy of this retina illness has substantially grown - this will be covered in this up-to-date multi-authored work. Apart from epidemiologically and genetically identified risk factors both the various pathophysiological aspects including the role of the complement system and clinical manifestations including OCT and angiographic characteristics are clearly represented. Furthermore, the different therapeutic approaches are presented and discussed, including proven procedures such as intravitreal anti-VEGF therapy and seeing-aid systems, in addition to the latest and upcoming methods in the area of pharmacology. The volume is well-illustrated and tables and summaries complete the presentation. From Books In Print
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| 4 | Artificial sight : basic research, biomedical engineering, and clinical advances / Mark S. Humayun ... [et al.] (eds.) | Springer | 2007 | WW270 A791 2007 | Advanced |
This book describes advances in implantable neural stimulation technology to restore partial sight to people who are blind from retinal degnerative diseases such as age-related macular degeneration and retintis pigmentosa. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The book summarizes the state of research and clinical practice in the field and reviews the current ideas and approaches of its leading researchers and practitioners. From Books In Print
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| 5 | Cell-based therapy for retinal degenerative disease / volume editors, Ricardo P. Casaroli-Marano, Barcelona, Marco A. Zarbin, Newark, NJ | Karger | 2014 | WW270 C393 2014 e-book | Advanced |
A unique source of the most currently available data presented by leading international experts In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading. From Books In Print
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| 6 | Evidence-based eye care / edited by Peter J. Kertes, T. Mark Johnson | LWW | 2014 | WW140 E93 2014 | Basic |
Now in a revised and updated Second Edition, this handy guide to eye care uses evidence from the latest clinical trials to deliver practical advice directly applicable to the challenges of daily ophthalmic practice. Helpful illustrations and tables support the text and improve outcomes. * Core content summarizes the major clinical trials in ophthalmology that support the current standard of care. * Practical focus helps readers apply research findings to day-to-day practice. * Logical organization guides readers from general epidemiology to disease-specific sections. * Broad scope addresses the full range of ophthalmologic subspecialties--from treatment of corneal defects, glaucoma, and cataracts to management of vitreo-retinal disorders. NEW in the Second Edition... * Results from the latest clinical trials let readers put current findings into practice. * Coverage of new pharmacologic agents broadens therapeutic choices. * Three new chapters address arterial occlusive disease, non-exudative age-related macular degeneration, and biostatistics. From Books In Print
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| 7 | Focus on macular diseases / [edited by] Sandeep Saxena | LWW | 2007 | WW270 F652 2007 | Basic |
Written by the foremost authorities from around the world, this full-color text describes and thoroughly illustrates state-of-the-art diagnostic and treatment modalities for macular disorders. Coverage begins with contemporary techniques for evaluation of the macula, including optical coherence tomography, microperimetry, and the multifocal electroretinogram. Chapters on outpatient and medical therapies cover laser treatment, intravitreal triamcinolone, and use of photodynamic therapy, transpupillary thermotherapy, anti-vascular endothelial growth factor drugs, and antioxidants for age-related macular degeneration. Internationally acclaimed experts describe surgeries for epiretinal membrane, vitreomacular traction syndrome, idiopathic macular hole, choroidal neovascularization, diabetic macular edema, myopic foveoschisis, and retinal vein occlusion. A DVD accompanying the book contains videos of eleven surgical procedures. From Books In Print
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| 8 | Fundus autofluorescence / edited by Noemi Lois, John V. Forrester | Wolters Kluwer Health/LWW | 2009 | WW270 F9895 2009 e-book | Advanced |
Featuring over 250 illustrations, this detailed full-color textbook provides up-to-date information on the use of fundus autofluorescence imaging in evaluation of retinal disease. Chapters describe the techniques available to image and quantify fundus autofluorescence and the autofluorescence patterns observed in the healthy eye and in various retinal diseases. Emphasis is on the value of fundus autofluorescence as a diagnostic and prognostic tool and its clinical utility in the context of other imaging techniques, such as fluorescein and indocyanine green angiography and optical coherence tomography. Each chapter also discusses the value of fundus autofluorescence in understanding the pathogenesis of the condition, and provides a comprehensive update on all aspects of the condition. A companion Website will offer the fully searchable text and an image bank. From Books In Print
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| 9 | Fundus fluorescein and indocyanine green angiography : a textbook and atlas / edited by Amar Agarwal | SLACK | 2008 | WW270 F981 2008 | Basic |
Fundus Fluorescein and Indocyanine Green Angiography: A Textbook and Atlas is a complete and detailed reference that comprehensively covers fluorescein angiography and the more recent and advancing indocyanine green angiography and their effectiveness in identifying and evaluating various retinal diseases. Dr. Amar Agarwal has teamed up with more than 30 retina specialists to provide eyecare professionals with the most current and essential information for the successful employment and accurate interpretation of these vital diagnostic tests. This timely reference uses a unique textbook and atlas format to convey its key points and includes over 400 images and photographs to provide a visual representation of the disease process. Sections include: Basics and principles; Macular diseases; Vascular retinal diseases; Non-vascular retinal diseases; and Optic nerve disorders. From Books In Print
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| 10 | Gass' atlas of macular diseases / Anita Agarwal | Elsevier Saunders | 2012 | WW17 G251s 2012 v.1-2 e-book | Basic |
The Fifth Edition of Gass' Atlas of Macular Diseases, by Dr. Anita Agarwal, provides expert diagnostic guidance on macular disorders and quickly brings you up to date on this evolving specialty. Using a case-based approach, it richly depicts a full range of retina and macular diseases, including new infectious, degenerative, and dystrophic conditions. Take advantage of the latest imaging technologies to identify common and rare disorders, and confirm difficult diagnoses with the aid of more than 5,500 high-quality images. From Books In Print
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| 11 | Medical retina / editors, Frank G. Holz, Richard F. Spaide | Springer | 2007 | WW270 M4897 2007 e-book | Basic |
The specialty of medical retina remains one of the most challenging fields in ophthalmology. Written by world-renowned experts, this authoritative work on medical retina is both comprehensive and practical and will serve the need of all ophthalmologists as well as optometrists and ophthalmic nurses to keep up-to-date with new developments in the important field of medical retina. It encompasses the application of confocal scanning laser ophthalmoscopy including fundus autofluorescence imaging as well as the mapping of central visual function by microperimetry. It also covers anti-VEGF therapy that has revolutionized the treatment of neovascular age-related macular degeneration. From Books In Print
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| 12 | OCT in AMD : optical coherence tomography in age-related macular degeneration : annual report of the French Ophthalmic Society / Gabriel Coscas ... [et al.] | Springer Medizin Verlag | 2009 | WW270 O209 2009 e-book | Advanced |
Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT. From Books In Print
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| 13 | Ocular angiogenesis : diseases, mechanisms, and therapeutics / edited by Joyce Tombran-Tink and Colin J. Barnstable | Humana Press | 2006 | WW140 O201 2006 | Basic |
Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches. From Books In Print
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| 14 | Retina / editor-in-chief, Stephen J. Ryan ... [et al.] | Saunders/Elsevier | 2013 | WW270 R4337 2013 v.1-3 e-book | Basic |
2013 BMA Medical Book Awards Highly Commended in Surgical Specialties Unequalled in scope, depth, and clinical precision, "Retina, 5th Edition" keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. The chapters demonstrate clarity, authority, and breadth which together with superb illustrations and videos result in an outstanding book. Reviewed by: B.R.Masters, Independent Scholar, From Books In Print
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| 15 | Retina / editors, Mitchell S. Fineman, Allen C. Ho | Wolters Kluwer Health/LWW | 2012 | WW17 R438 2012 | Basic |
Color Atlas And Synopsis Of Clinical Ophthalmology -- Wills Eye Institute -- Retina is part of a series developed by Philadelphia's famed Wills Eye Institute. In this 2nd edition we've combined short, succinct text with over 400 illustrative photographs to provide the most comprehensive, yet easily accessible resource covering all the major aspects of vitreoretinal disease. Written to be a "go-to" field manual rather than an encyclopedic reference this atlas provides an up-to-date clinical overview of all the major areas of ophthalmology including, epidemiology and etiology, history, physical examination, differential diagnosis, laboratory and special examinations, diagnosis, prognosis, and management. This color atlas and synopsis will be an excellent resource for students, residents, and practitioners in all healthcare professions when it comes to the diagnosis and management of vitreoretinal diseases and the care of patients who suffer from these conditions. From Books In Print
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| 16 | Retinal and choroidal angiogenesis / edited by J.S. Penn | Springer | 2008 | WW270 R4384 2008 | Basic |
Retinal and choroidal angiogenesis are the leading causes of irreversible vision loss in developed countries. For this reason, ocular angiogenesis is an intensely studied process, and the field is advancing at an astounding pace. It has become increasingly difficult to manage the vast amount of information generated by the growing group of interested investigators, thus a resource is needed that distills and summarizes our progress to date. Additionally, novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. Retinal and Choroidal Angiogenesis emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance. The result is a reference work appealing to ophthalmologists interested in clinical applications, as well as to basic scientists interested in the cellular and molecular mechanisms of angiogenesis, both in the context of ocular and non-ocular conditions. From Books In Print
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| 17 | Retinal angiography and optical coherence tomography / edited by J. Fernando Arevalo | Springer | 2009 | WW270 R438045 2009 e-book | Advanced |
This superbly practical book has been written by expert authors and is an ideal resource for clinicians seeking practical "how-to" information on OCT. OCT is a relatively new imaging technique that is becoming increasingly popular among ophthalmologists in both private and academic settings. Imaging has been a slow moving area in ophthalmology for some time, but now OCT is providing another, more detailed source of demonstrable change in the eye, in diagnostic, therapeutic or post-surgical setting. OCT and ultrasound both measure advancing disease states and post-surgical healing. The difference is that OCT shows more subtle changes, particularly post-surgically. From Books In Print
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| 18 | Retinal vascular disease / A.M. Joussen ... [et al.] (eds) | Springer | 2007 | WW270 R611 2007 | Basic |
Vascular diseases of the retina are a major cause of blindness among all age groups. Edited and written by internationally well-known experts, this state-of-the-art comprehensive overview of basic and clinical science will enhance the understanding of retinal vascular disease and help in the evaluation of current and future treatment approaches for the clinician. The well-structured and highly illustrated text is divided into three easy-to-follow sections. This unique textbook-atlas also includes topics which are not currently found in other retinal disease textbooks, such as case reports and clinical follow-ups. From Books In Print
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| 19 | Stem cell research and therapeutics / Yanhong Shi, Dennis O. Clegg, editors | Springer | 2008 | QU325 S82393 2008 | Advanced |
This updated reference covers current knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine applications for many human diseases including cardiovascular diseases, neurological disorders and liver degeneration. From Books In Print
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| 20 | Stem cells and regenerative medicine / editors, Walter C. Low, Catherine M. Verfaillie | World Scientific | 2008 | QU325 S82345 2008 e-book | Advanced |
Stem cells have the ability to differentiate into cells that are found throughout the body. This fundamental property of stem cells suggests that they can potentially be used to replace degenerative cells within the body, and regenerate the functional capacity of organ systems that have deteriorated because of disease or aging. This authoritative textbook provides an overview of the latest advances in the field of stem cell biology, spanning topics that include nuclear reprogramming, somatic cell cloning, and determinants of cell fate; embryonic stem cells for hematopoietic and pancreatic repair; adult stem cells for cardiovascular, neural, renal, and hepatic repair; and manufacturing of stem cells for clinical use. Book jacket. From Books In Print
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| 21 | Stem cells in ophthalmology / editors, Daniel H. Scorsetti, Victor L. Perez, Jose Alvaro Pereira Gomes | Jaypee-Highlights Medical | 2015 | WW168 S8247 2015 | Advanced |
Stem Cells in Ophthalmology describes a wide range of therapeutic applications of stem cells in ophthalmological treatments. This book is written and edited by distinguished international authors, who have drawn heavily on their in-depth academic knowledge, practical experience and research. Comprised of 17 chapters, the book initially covers basic stem cell biology and immunity, proceeding to detail the use of stem cell therapy to regenerate all the structures of the visual system and ocular adnexa. Immunologic factors, such as antigen identification and functional rejection pathways are discussed in detail. The book also details practice of translational medicine and facilities, and governmental requirements needed to establish an ocular stem cell program. Stem Cells in Ophthalmology gives extensive coverage to the regenerative use of stem cells in ophthalmology. Enhanced by 84 colour images and illustrations, this is an essential resource for ophthalmologists and stem cell therapists. From Books In Print
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| 22 | Stem cells in regenerative medicine / edited by Julie Audet and William L. Stanford | Humana | 2009 | QU25 S824 2009 e-book | Advanced |
As regenerative medicine involves replacing diseased cells, tissues or organs, or repairing tissues in vivo, the manipulation of stem cells underlie its goals. In Stem Cells in Regenerative Medicine: Methods and Protocols, leading experts in the field provide an updated representation of the landscape of stem cell-based therapies in a wide spectrum of tissue systems and ontogenic stages, from the isolation and culture of stem cells to their actual use in vivo. Written in the highly successful Methods in Molecular Biology series format, these chapters include brief introductions to the topic, lists of the necessary materials and reagents, readily reproducible, step-by-step laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Comprehensive and easy-to-use, Stem Cells in Regenerative Medicine: Methods and Protocols is certain to contribute greatly to the definition of standardized procedures for the manipulation of somatic and embryonic stem cells in research and clinical applications." From Books In Print
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| 23 | Stem cells to model and treat disease / [edited by] Sheila Chari ... [et al.] | APCell/ Elsevier | 2014 | QU325 S82475 2014 | Advanced |
Stem Cells to Model and Treat Disease' provides in-depth and up-to-date reviews on the myriad ways that stem cells are being used to better understand and treat human disease. This publication offers essays from leaders in the stem cell field on some of the most important questions being faced in clinics and research labs, including the safety and efficacy of stem cell treatments, the use of stem cells to regenerate organs, the use of reprogrammed stem cells to model and treat disease, and the use of stem cells in clinical applications such as HIV disease and stroke. From Books In Print
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| 24 | The retina and its disorders / editors, Joseph C. Besharse, Dean Bok | Elsevier/Academic Press | 2011 | WW270 R43842 2011 | Basic |
This selection of articles from the Encyclopedia of the Eye covering retina, optics/optic nerve and comparative topics constitutes the first reference for scientists, post docs, and graduate students with an interest beyond standard textbook materials. It covers the full spectrum of research on the retina - from the basic biochemistry of how nerve cells are created to information on neurotransmitters, comparisons of the structure and neuroscience of peripheral vision systems in different species, and all the way through to injury repair and other clinical applications. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of the retinaChapters arecarefully selected from the "Encyclopedia of the Eye" by one of the world's leading vision researchersThe best researchers in the field provide their conclusions in the context of the latest experimental results" From Books In Print
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| 25 | Trends in stem cell biology and technology / Hossein Baharvand, editor | Humana | 2009 | QU325 T7942 2009 e-book | Advanced |
Stem cells, characterized by the ability to both self-renew and to generate diff- entiated functional cell types, have been derived from the embryo and from va- ous sources of the postnatal animals and human. The recent advances in stem cell research have led to a better understanding of self-renewal, maintenance, and diff- entiation of both embryonic and somatic stem cells. This has significantly increased our knowledge of cellular and developmental biology in general and will certainly continue to do so for a long time to come. Moreover, given their role in maintaining and replenishing tissues, stem cells represent a potential means of restoring tissue function and thereby treating the root cause of degenerative disease. Therefore, in parallel, we need to improve our cognizance of the challenges involved in applying stem cells in clinical settings. From Books In Print
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| 26 | VEGF in development / [edited by] Christiana Ruhrberg | Springer Science+Business Media | 2008 | QU107 V422 2008 e-book | Basic |
This book covers vascular endothelial growth factor A (VEGF or VEGFA), a secreted signaling protein. It highlights the central importance of this growth factor for vertebrate development. From Books In Print
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| 27 | Visual prosthesis and ophthalmic devices : new hope in sight / edited by Joyce Tombran-Tink, Colin J. Barnstable, Joseph F. Rizzo III | Humana | 2007 | WW358 V834 2007 e-book | Advanced |
This volume details the latest technology in treating eye injuries and infections. It provides insight into the most up-to-date and established treatment options. The volume focuses on what can currently be achieved with a variety of ocular prostheses as well as what the future holds. Coverage reviews issues such as intraocular lens implants, biocompatibility of materials, retinal implants, testing models, and software designs. From Books In Print
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