心血管疾病是現代化社會的重要健康問題，在臺灣地區，心血管疾病已連續數年蟬連國人十大死因的前幾名。肥胖、代謝症候群(metabolic syndrome)及糖尿病都是心血管疾病的重要危險因子，糖尿病甚至被視為「等同冠狀動脈心臟病」(coronary artery disease equivalent)。此外，肥胖、代謝症候群及糖尿病也被認為與癌症有關。其他的人類健康領域，如神經科、精神科、眼科、肝膽科、外科等也無不與此息息相關。因此無論是臨床照護或基礎研究皆須積極投入，以達到預防心血管疾病及其他相關併發症之終極目標。所以研究課題著重在此類疾病的成因、遺傳學，與胰島素阻抗(insulin resistance)及併發症相關之病理生理、生物標誌(biomarker)、訊息傳遞、分子生物學研究。另一方面，開發治療此類疾病及其併發症之藥物，也是全球健康產業界朝思暮想的課題。
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|編號||書名 / 作者||出版社||出版年||索書號||適用等級||摘要|
|1||Atlas of diabetes / editor, Jay S. Skyler ; with 31 contributors||Current Medicine||2006||WK17 A8808 2006||Basic||
The third edition of the Atlas of Diabetes presents over 750 vivid illustrations, clinical photographs and instructive diagrams and charts, all with detailed legends.
The incomparable images contained in this atlas relate to all aspects of diabetes, including prevention, management, complications, and the newest treatment options available.
|2||Cardiovascular biomarkers : pathophysiology and disease management / edited by David A. Morrow ; foreword by Elliot Antman||Humana||2006||WG210 C2684 2006 e-book||Basic||Synopsis/Annotation Cardiovascular Biomarkers：Pathophysiology and Disease Management is aimed at meeting the needs not only of the practicing clinician but also the interests of clinician-scientists, medical trainees and laboratorians. The book is divided into seven sections, each of which covers a major class of biomarkers (e.g. biomarkers of necrosis, biomarkers of inflammation, and biomarkers of hemodynamic stress). Each section begins with an overview of the biology and development of each major class, followed by a concise review of analytic issues important to the clinician, and then by a series of chapters written by internationally recognized experts who discuss clinical applications of the biomarkers. These later chapters focus on the incorporation of biomarkers into the contemporary management of patients with cardiovascular disease, emphasizing clinical studies, evidence-based diagnostic algorithms, and critical pathways for triage and therapy.|
|3||Cecil textbook of medicine / edited by Lee Goldman, Dennis Ausiello||Saunders||2004||WB100 C3888 2004||Basic||
Goldman & Ausiello: Cecil Textbook of Medicine (Single Volume), 22nd ed.
By Lee Goldman, MD, Julius Krevans Distinguished Professor and Chairman, Department of Medicine, Associate Dean for Clinical Affairs, University of California, San Francisco School of Medicine, San Francisco, CA; and Dennis Ausiello, MD, Department of Medicine, Massachusetts General Hospital, Boston, MA
Cecil's Textbook of Medicine has been one of the world's most trusted medical references since its original publication in 1927. In the 22nd edition of this classic text, more than 450 renowned authorities present the very latest clinic knowledge augmented by a superb new full 4-color design and internal navigation system. Here you'll continue to find comprehensive coverage of the scientific foundations and biological basis of disease processes; an introduction to clinical practice protocols; current concepts of pathophysiology, diagnosis, and treatment -- all presented by distinguished experts in a new user friendly, graphically appealing 4-color format. The core of the text continues to encompass the disorders of the major organ systems, including the approach to the patient, clinical manifestations, diagnostic procedures, and treatment strategies. Text includes a bonus CD-ROM with full text and images with a link to the website.
New to edition
A new section on clinical pharmacology provides sound theoretical basis for pharmacotherapy critical to medical practice
New evidence-based medicine summaries in therapy sections provide Grade A (randomized controlled trial) evidence, including reference sources, for the leading current therapeutic and management recommendation.
The expanded oncology section provides thorough coverage of all key cancers, including completely new coverage of some cancers (eg, testicular cancer)
New full 4-color design permits the addition of hundreds of new color photos as well as the integration of old photos into the text at the appropriate point (rather than as color plates far away from the chapter)
Unique internal navigation system, including diagnostic and 'clinical syndrome' algorithms and treatment summary tables designed for optimal and timely retrieval of information
Comprehensive coverage of pathogenesis (including molecular genetics), diagnosis, and therapy to explain "why" behind the "how"
Flow diagrams facilitating the best approach to diagnosis and treatment of the most common complaints and diseases
|4||Diabetes and cardiovascular disease / edited by Michael T. Johnstone, Aristidis Veves||Humana||2005||WK835 D53345 2005 e-book||Basic||
From the Publisher
On the basic side, this book describes the pathophysiology of diabetic vascular disease and the methods are included to evaluate them. This book describes recent clinical study findings that Dr. Johnstone discusses in his own chapter. Diabetes and Cardiovascular Disease is in Humana's Contemporary Cardiology Series and covers the subject categories of Cardiology, Endocrinology and Diabetes, Internal Medicine and Physiology. Readership includes cardiologists, internists, vascular specialists, diabetologists, endocrinologists and family physicians.
From the Author
This book will be essential reading for all cardiologists, general internists, vascular specialists as well as medical students who are confronted with patients who have diabetes and cardiovascular disease. Covered are reviews of clinical aspects of diabetic cardiovascular disease, up-to-date clinical and scientific survey of the basic mechanisms of diabetic damage, full discussion of microvascular effects of diabetes mellitus and examination of diabetes' effects on the heart, including atherosclerosis and congestive heart failure.
|5||Diabetes mellitus : a fundamental and clinical text / editors, Derek LeRoith, Simeon I. Taylor, Jerrold M. Olefsky||Lippincott Williams & Wilkins||2004||WK810 D536r 2004||Basic||Synopsis/Annotation Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.|
|6||The diabetic kidney / edited by Pedro Cortes, Carl Erik Mogensen||Humana||2006||WK835 D5358 2006||Basic||Synopsis/Annotation This book discusses the complications of diabetes that in most cases leads to end stage renal disease within 3-6 years. the Diabetic Kidney is divided into two parts, Basic Pathophysiology and Biochemistry of Diabetic Nephropathy and Clinical Aspects of Diabetic Nephropathy. focusing heavily on mechanisms, this book aims to provide a different focus on diabetic nephropathy.|
|7||Evidence-based endocrinology / edited by Victor M. Montori||Humana Press||2006||WK140 E92 2006||Basic||SciTech Book News ( June 01, 2006 ) Montori (endocrinology, diabetes, and internal medicine, Mayo Clinic College of Medicine) assembles essays that connect evidence-based medicine--using evidence from medical research--to endocrinology. The contributors, an international group from diverse medical fields, describe the past, present, and future of evidence-based medicine; practicing it in terms of endocrinology; research evidence; and case studies. Topics include using evidence in clinical diagnosis, patient participation in decision-making, health policy decisions, observational studies, systematic reviews, quality of life assessment, and case studies of diabetes, hypoglycemia, obesity, osteoporosis, and chronic fatigue syndrome. The book is aimed at endocrinologists, internists, and those in general medicine. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)|
|8||Fed up! : winning the war against childhood obesity / Susan Okie||Joseph Henry||2005||WD212 O41f 2005||Basic||
From the Publisher
Once dismissed by the medical profession as a purely cosmetic problem, obesity represents an ominous health threat for our children. Obesity is now second only to smoking as a preventable cause of death. Without early intervention, overweight children often become overweight adults - and we know that at any age obesity can lead to diabetes, high cholesterol, high blood pressure, heart disease, depression, and other life-threatening conditions. Diabetes and heart disease alone cause more than 780,000 deaths each year. In fact today's kids may be the first generation in U.S. history to have a shorter life expectancy than their parents.
In his introduction, well-known pediatrician Dr. T. Berry Brazelton discusses childhood obesity as a US epidemic. Dr. Okie, a family physician/medical journalist, addresses the trends that have resulted in "the fattest generation," and ways that schools and the community can help children reduce the risk of diabetes, heart disease, and reduced life expectancy. She includes resources. Annotation ©2004 Book News, Inc., Portland, OR
|9||Handbook of diabetes management / edited by Donna Zazworsky, Jane Nelson Bolin, Vicki B. Gaubeca||Springer||2006||WK810 H236 2006||Basic||
From the Publisher
Over 18 million Americans are afflicted. Nearly as many are at risk. Diabetic conditions account for one-fifth of the nation's chronic health care burden. A public health crisis of this magnitude demands professional resources that apply evidence-based practical knowledge and anticipate the challenges that lie ahead. The Handbook of Diabetes Management is one such reference, addressing the complexity of the disease, the diversity of the populations it affects, and the continued improvement of care systems.
◎The latest findings on management and treatment-medication, nutrition, exercise, alternative
therapies-plus patient self-care and behavioral issues
◎An accessible overview of diabetic origins and disease processes
◎Up-close coverage of specific patient populations, including Latinos, Native Americans, rural
communities, and the uninsured
◎In-depth discussion of prediabetes, gestational diabetes, and foot conditions
◎An assortment of invaluable tools, from depression assessment instruments to critical reviews of
◎Salient chapters on policy, regulatory, funding, marketing, and media issues
◎Innovative case studies from successful, replicable programs
|10||Handbook of obesity : clinical applications / edited by George A. Bray, Claude Bouchard||M. Dekker||2004||WD210 H236 2004||Basic||
From the Publisher
Written by an outstanding group of internationally recognized scientists representing North America, Europe, Asia, and Australia, this up-to-date overview of obesity, its research, and clinical components details topics ranging from historical perspectives, definitions, and measurement to etiology, pathophysiology, prevention, and treatment. Generously furnished with nearly 7500 references, tables, equations, drawings, and photographs, this exhaustive guide is a useful resource for physiologists, nutritionists, endocrinologists, bariatricians, dietitians, obesity research scientists, pharmaceutical researchers, psychiatrists, and graduate and medical school students in these disciplines.
|11||Handbook of obesity : etiology and pathophysiology / edited by George A. Bray, Claude Bouchard||Marcel Dekker||2004||WD210 H236 2004||Basic||SciTech Book News ( March 01, 2004) Reflecting the myriad developments in the field, the second edition (first: 1998) is now in two volumes, sold separately. This, the initial volume, covers prevalence, etiology, and consequences; (the second volume is devoted to evaluation, prevention, and treatment). There are new chapters on the fetal origins of obesity; the economic costs, mainly in the English-speaking world; new approaches in pharmaceutical research based on genetic and molecular biology; primate studies; related issues from treatment of AIDS; and the metabolic syndrome in predicting health risk. Other topics include regulation of food intake, adipose tissue (5 chapters), endocrine gland function (3 chapters), and energy expenditure (3 chapters). The chapters are written by specialists, most in the US, but also in France, the UK, Australia, Sweden, Canada, Italy, and Germany. The editors are with the Pennington Biomedical Research Center at Louisiana State U. in Baton Rouge. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)|
|12||Insulin resistance : insulin action and its disturbances in disease / editors, Sudhesh Kumar, Stephen O'Rahilly||J. Wiley||2005||WK820 I59608 2005||Basic||From the Publisher In this book, several leading investigators who have made seminal contributions to the field have written chapters covering the normal biology of insulin action, the pathophysiology of insulin resistance, the myriad clinical consequences of insulin resistance, and finally, current and future prospects for its treatment. The book therefore not only provides an up-to-date perspective of the subject from several of the leading thinkers in the field, but should also serve as a useful source of reference for students, researchers and clinicians. Synopsis Kumar (diabetes, University of Warwick Medical School, UK) and O'Rahilly (clinical biochemistry, University of Cambridge Addenbrooke's Hospital, UK) collect work by leading investigators who have made seminal contributions to the field, to present the latest progress in the understanding of the normal biology of insulin action, the pathophysiology of insulin resistance, genetic and environmental factors that result in resistance, clinical consequences, and current and future prospects for treatment. The book will serve as a reference for students, researchers, and clinicians.|
|13||Isotope tracers in metabolic research : principles and practice of kinetic analysis / Robert R. Wolfe, David L. Chinkes||Wiley-Liss||2005||QU120 W855i 2005||Basic||
From the Publisher
This book offers the most thorough practical and theoretical treatment of tracer methodology as applied to the study of metabolic processes. It integrates biochemical, physiological, mathematical, and analytical aspects, with a focus on radioactive and stable isotopes in biomedical research. The authors systematically present complete information on how to perform these studies, from tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions have been added to highlight key points in each chapter. The contents have been fully updated and reorganized to enhance its utility, with notable expansion of coverage on protein metabolism and a brand new chapter on nuclear magnetic resonance (NMR).
|14||Obesity and diabetes / edited by Christos S. Mantzoros||Humana Press||2006||WK835 O12 2005||Basic||From the Publisher This text aims to be a comprehensive review of the research and clinical aspects of obesity and diabetes. The 31 chapters presented by Mantzoros (endocrinology, Harvard Medical School) begin with a review of the history and epidemiology of the conditions. The next section focuses on genetics and pathophysiology and reviews known mechanisms and interactions. The next 16 chapters discuss the diagnosis, clinical manifestations, and complications associated with obesity and diabetes. The final seven chapters present such treatment approaches and diet and lifestyle change, exercise and behavioral approaches, medical approaches to patients with obesity and patients with obesity and type two diabetes, surgical treatment of obesity and diabetes, and future developments in pharmacology. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)|
|15||Obesity prevention and public health / edited by David Crawford and Robert W. Jeffery||Oxford University||2005||WD210 O1258 2005||Basic||
From the Publisher
More than 22 million children under five are now obese or overweight. Globally, an estimated 10% of school-aged children, between five and 17 years old, are overweight or obese, and the situation is getting worse. Although recognised clinically for some time as an important condition that increases risk of ill-health in affected individuals, it is only recently, that obesity has been recognised as a population-wide problem that requires preventive action. Obesity is a major contributor to diseases and disability, the associated health
costs are enormous, obesity has already reached epidemic proportions in many countries, and incidence is continuing to increase in children and adults. Disturbingly the epidemic is not confined to developed countries, with many developing countries and those in transition affected. While recognised as a major population health problem, our understanding of the causes of the epidemic is poor, there has been relatively little population-based research that has focused on the prevention of unhealthy weight gain, and as a consequence knowledge regarding how and where best to intervene is limited. This book draws together the existing literature and expertise and with a view to helping set the agenda for public health action.
|16||Office management of obesity / [edited by] George A. Bray||Saunders||2004||WD210 O32 2004||Basic||
From the Publisher
This book addresses the prevalence and risks of obesity and how primary care physicians should approach evaluation and treatment for the obese patient. Chapters include succinct explanations on the prevalence of obesity, how food intake leads to weight gain, and how the primary care physician should treat the obese patient, including new drug therapies, the risks and benefits of herbal preparations, and behavioral modifications. George Bray is a renowned expert in the field of obesity, and has brought many of obesity's "big players" into the book as contributors. The chapters are current, concise, and review the most relevant information in the field.
Contributions from world experts in obesity research and treatment reflect the current "best practice" in obesity.
|17||Pediatric endocrinology : mechanisms, manifestations, and management / edited by Ora Hirsch Pescovitz, Erica A. Eugster||Lippincott Williams & Wilkins||2004||WS330 P37145 2004||Basic||
Doody Review Services
Reviewer: Robert Cunningham, Nephrology (Ochsner Clinic Foundation)
Description: This is a comprehensive book that provides a review of the basic science of pediatric endocrinology and an approach to both the diagnosis and treatment of pediatric endocrine disorders.
Purpose: The authors state in the preface that they aim to provide in-depth coverage of the basic science underlying their field and a comprehensive approach to the clinical management of patients who have these disorders. This book is a timely one and covers a large number of disorders; the reader will be able to initiate an evaluation of a number of pediatric endocrine disorders and the rationale for treatment strategies is well documented.
Audience: The book is aimed at pediatric endocrinologists, pediatricians, residents, and students who care for children with endocrine disease. The authors also hope it will be of help to other health professionals who are involved with the care of these children. In this regard, it succeeds as a source for pediatric endocrinologists and as a reference for the pediatrician and resident physician. The discussion of molecular mechanisms and testing is too detailed to be generally helpful to other health professionals with the exception of those internist endocrinologists who will be comfortable with the science as discussed.
Features: The book begins with a section on genetic disorders in pediatric endocrinology, reviews basic concepts in genetics, and presents evidence regarding gene defects that have been identified which result in endocrine dysfunction. This section is clearly meant for a review; in a 3-page span, 27 genetic mutations are identified and discussed. This section is well referenced and well illustrated. The next section covers diagnostic tests that are used in endocrinology and discusses both radiological procedures and the newer molecular techniques. Subsequent sections cover disorders of growth, thyroid adrenal disease, glucose homeostasis, bone metabolism, sexual differentiation and maturation, and nutrition. The final chapters cover multiple endocrine disorders and the endocrine aspects of stress.
Assessment: This first edition book competes with Pediatric Endocrinology, edited by Mark A. Sperling, whose second edition was published in 2002. The books have similar aims and for the physician familiar with pediatric endocrinology, they are of similar value. I suspect that the Pescovitz is better for the novice such as the pediatric resident or general pediatrician who has not been exposed to the basic science underlying the newer diagnostic techniques. It is more understandable and the illustrations are helpful in explaining the science that is involved. As such, this is an excellent book for the pediatric resident with an interest in endocrine disorders and would be a useful reference in the general pediatrician's office.
|18||Preventing childhood obesity : health in the balance / Committee on Prevention of Obesity in Children and Youth, Food and Nutrition Board, Board on Health Promotion and Disease Prevention ; Jeffrey P. Koplan, Catharyn T. Liverman, Vivica I. Kraak, editors||National Academies||2005||WD210 I604p 2005||Basic||
From the Publisher
Preventing Childhood Obesity provides a broad-based examination of the nature, extent, and consequences of obesity in U.S. children and youth, including the social environmental medical and dietary factors responsible for its increased prevalence. The book also offers a prevention-oriented action plan that identifies the most promising array of short-term and long-term interventions as well as recommendations for the roles and responsibilities of numerous stakeholders in various sectors of society. Preventing Childhood Obesity explores the underlying causes of this serious health problem and the actions needed to initiale, support, and sustain the societal and lifestyle changes that can reverse the trend among our children and youth.
|19||Preventive cardiology : a practical approach / editor-in-chief, Nathan D. Wong ; associate editors, Henry R. Black, Julius M. Gardin||Medical Pub. Division||2005||WG210 P8955 2005||Basic||
From the Publisher
This practical reference blends a readable summary of the vast literature on cardiovascular disease epidemiology with clear, evidence -based, patient-oriented strategies for screening, identifying, and controlling cardiovascular risks.
Wong (heart disease prevention, University of California-Irvine) supplies health care providers with a wealth of information relating to the identification and management of key risk factors of atherosclerotic cardiovascular disease and the development of a preventive cardiology clinic. This second edition contains updated material on recent trends in cardiovascular disease, new methods for risk assessment and screening, the latest findings from clinical trials and their implications, and newly released guidelines for control of hypertension, dyslipidemia, and other risk factors. Annotation ©2004 Book News, Inc., Portland, OR
|20||Stem cells in endocrinology / edited by Linda B. Lester||Humana Press||2005||WK140 S824 2005 e-book||Basic||
From the Publisher
In Stem Cells in Endocrinology, leading stem cell biologists and developmental endocrinologists critically review both cutting-edge approaches to stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver- associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases.
|21||The foot in diabetes / edited by Andrew J.M. Boulton, Peter R. Cavanagh, Gerry Rayman||Wiley||2006||WK835 F6872 2006||Basic||Synopsis/Annotation This latest edition reviews important developments in the field of diabetic foot care and its scientific basis. With a focus on practical applications and management it examines new technologies such as vacuum therapy, new casting techniques, the use stems cells and gene therapy in wound healing and reviews new international guidelines introduced for the management of infectious disease. Since the publication of the third edition of The Foot in Diabetes, there have been important developments in the field of diabetic foot care and its scientific basis, including: The introduction of new technologies such as vacuum therapy, new casting techniques, the use of hormones and growth factors in wound healing; Advances in the understanding of the biomechanics of foot problems; Increased problems with multidrug-resistant organisms; The introduction of new international guidelines for the management of foot infections; Significant progress in the use of cytokines, metalloproteinase inhibitors, stem cells and gene therapy in wound healing. This fourth edition of this popular title maintains the strengths of earlier editions, with a strong emphasis on practical applications and management. All the chapters have been fully revised and updated, with new chapters introduced to cover the topics listed above. This book features more international contributors, giving it more global relevance than before, and for the first time it includes colour plates. With its focus on practically oriented advice, this book will be essential reading for all members of the diabetes specialist team including diabetologists, podiatrists, specialist nurses, general practitioners, surgeons and clinical researchers.|
|22||Unstable and brittle diabetes / edited by Geoff Gill||Taylor & Francis||2004||WK810 U59 2004||Basic||Synopsis/Annotation Controversial in terms of definition and management, brittle diabetes is a difficult area for diebetologists. Bringing together the latest research, Unstable and Brittle Diabetes provides a comprehensive overview that helps the reader understand this complex and troublesome condition. Topics include history of our knowledge of the disease, an overview of the disease, secondary causes, hypoglycaemic diabetic instability, insulin resistance and over-insulinisation, diabetic instability in children and the elderly, psychological factors and intervention, educating patients about the disease, causes, outcomes, treatment, how to live with the disease, and more. Unstable and Brittle Diabetes brings together the latest research on the management of brittle diabetes which is a controversial area in terms of definition and management. This monograph will help the dibetologist understand this troubling condition. In this text, the author brings together the latest research on the management of brittle diabetes or 'erratic glucose control', which is a controversial area in terms of definition and management. This monograph has been produced to help the diabetologist understand this troublesome condition.|